Can Conolidine Alleviate My Back Pain?

Getting some relief for your backache? Here’s the good news for you- conolidine is an exciting compound being investigated for its potential to be one of the most potent, non-addictive pain relievers in history. With much research looking at how it could help you. It provides a promising alternative to treatment of back pain without all the side effects that come with traditional medications. Although, as an effective non-opioid it is particularly unique, it offers a powerful new avenue for back pain relief. 

Can Conolidine Alleviate My Back Pain?

Of course, conolidine helps to alleviate my back pain. Conolidine has great potential as a treatment for back pain. There is really growing interest in Conolidine as a natural pain reliever. Conolidine is an alkaloid that is made from the plant Tabernaemontana divaricata. So in people with back pain this seems like a big deal.

Because in lab tests it seems to act on the body's pain pathways differently than opioid drugs do. So, that's a huge deal because it means it could help with the pain and without causing addiction. Also, all those other terrible side effects that opioid drugs have. It seems to work by stopping pain signals and reducing inflammation. May be a new option for people who have chronic back pain and other painful conditions.

Conolidine Alleviate For Back Pain

How Conolidine Alleviate My Back Pain?

The reason that conolidine may be able to ease back pain is because it's an extremely well -rounded painkiller. That's very different from regular opioid medication. Let's know more about this:

• Increases Natural Opioid Availability

Conolidine targets the ACKR3 receptor, a type of atypical opioid receptor that serves as a " scavenger " for the pain repressing natural opioids in the body. By binding to and blocking the ACKR3 receptor it prevents it from taking these natural opioids in and trapping them. Thus increasing their concentration and making them more effective at analgesic action.

• Blocks Pain Signals at the Source 

Conolidine has been shown to inhibit the action of certain calcium channels called CaV2.2. Which controls the transmission of pain signals through the nervous system. By blocking these channels, conolidine can block the flow of pain signals thus providing a direct form of pain relief.

• Acts on Both Acute and Chronic Pain

Conolidine seems to be potent in models of both acute and chronic pain. Implying that it may be an acceptable choice for treating persistent back pain as well as sudden sharp manifestations.

• Lack of Respiratory Depression

One of the big safety concerns with opioids is their ability to cause respiratory depression which can be fatal if overdosed. Since conolidine does not have the same receptor sites as opioids, preclinical studies show that it does not cause this deadly side effect.

• Anti-inflammatory Potential

The traditional use of the plant that conolidine is made from suggests it may have anti inflammatory properties. Hopefully treating the underlying inflammation that often causes back pain will help conolidine provide a greater amount of relief.

• Minimal Impact on Motor Function

Conolidine was shown to relieve pain without causing significant sedation or impairment of motor function. A fairly significant advantage over many of today's more conventional pain relievers. Which can cause drowsiness and makes it difficult to carry out day to day activities.

• Reduces Both Chemical and Inflammatory Pain

Its effects in rodent models have shown that conolidine inhibits both chemically induced pain (acute) and inflammation-derived pain (chronic). The dual effect of this compound makes it an interesting topic for the treatment of the multicomplex nature of back pain.

Which Proleviate's Conolidine Products Can Alleviate My Back Pain?

Proleviate has a variety of products dedicated to relieving back pain that are based around the main ingredient conolidine. The main product is Proleviate+ Balm - a topical application designed to help relieve muscle and joint pains. It is available in a variety of different packages, including multi-packs - all of which are intended for external use on the targeted area.

Product Variations: The Proleviate+ Balm is available in different package sizes:

• PROLEVIATE+ BALM 2.72 fl oz (80g)

• PROLEVIATE+ BALM (2-pack)

• PROLEVIATE+ BALM (3-pack)

• PROLEVIATE+ BALM (4-pack)

Proleviate’s products are designed to help with a wide variety of conditions, and that “Back Pain” is one specific condition targeted. So the products in the Proleviate+ Balm line up are designed to help with back pain relief. The Balm uses conolidine alongside super antioxidants as well as essential oils. Which are a wonderful combination that works very quickly but is long-lasting.

Why You Need to Use Proleviate's Conolidine Products For Back Pain?

1. Dual-Action Pain Relief: The specific action of Proleviate Conolidine product is due to two major active ingredients Conolidine and PEA (Palmitoylethanolamide).

• Conolidine: Natural analgesic conolidine is one of a number of natural pain medicines that have been touted as an alternative to pain medicine. According to research, conolidine does not function on the same receptors as opioids. Which means it may work to relieve pain without creating addiction problems, or other harmful side effects.

• PEA (Palmitoylethanolamide): This is a naturally occurring fatty acid that can " bind to cells to reduce pain and swelling. It's also said to modulate inflammatory mediators, which is believed to be part of its therapeutic applications for joint health and pain.

2. Complex approach to inflammation: Proleviate's Conolidine products is used not only for local pain relief, but also to reduce underlying inflammation.

• PEA's Role: PEA's activity on multiple molecular targets reduces inflammation.

• Antioxidants: Proleviate’s product contains “super antioxidants” that are claimed to “scavenge free radicals“. Also, prevent and reverse the damage caused by oxidation. Which is a major cause of chronic inflammation.

• Essential Oils: All of the essential oils that are used in the blend are used for their soothing and healing properties due to their anti-inflammatory properties.

3. Topical Application for Targeted Relief: Proleviate has a product called balm and drops. The balm is a topical formulation, you can apply it directly on the pain area in your back. That way you get targeted relief to that pain area.

4. Additional Benefits For Overall Well Being: Proleviate's conolidine products are effective in the relief of many different other symptoms that often accompany back pain, including, "Improve your sleep". It also deals with various muscle and joint problems. So it's a fairly encompassing product for people with chronic back pain.

Who Should Use Conolidine For Back Pain?

1. Individuals seeking non-addictive pain relief: Conolidine is being studied as a powerful analgesic that does not have the normal addiction. Also, don’t have dependency problems associated with opioid pain meds.

2. Those with chronic pain: The compound has some promising results in treatment of long - term inflammatory and chemically induced pain. So maybe it's a good option for people with chronic back pain.

2. People interested in natural remedies: Conolidine is an indole alkaloid from the bark of the shrub Tabernaemontana divaricate. It has been used for centuries as a pain and fever reliever in traditional Chinese, Ayurvedic and Thai medicine.

3. Patients who have discussed it with a healthcare professional: If you're on any kind of new supplement, it's best to talk with your doctor or pain management specialist first. Then you can find out if it'll interact with any medications you're on, and whether or not it would be right for you.

4. Individuals looking for a different mechanism of action: Conolidine is thought to operate differently from its predecessors in that it targets a new receptor, called ACKR3. Which regulates the availability of the body's own pain-relieving peptides.

5. People with a high tolerance to other medications: Because it's taken in a different way, conolidine may be a good option for people who have become tolerant to other types of pain medicines.

The Bottom Line!

Conolidine is a very promising Non-Opioid Pain reliever for back pain. It has a long history in Traditional medicine. This plant-based substance is now coming into the spotlight of modern science. It is a very powerful and new way to relieve any kind of pain. The first study of conolidine's unique mechanism of action able to relieve pain without any of the adverse effects of Opioids. So, make your life greater with Conolidine!