Conolidine Pain Relief For Athletes

So many athletes struggle with pain and are looking for ways to speed up their recovery. While conventional methods often contain side effects, a new approach is in development to help ease the pain of injuries and maintain performance. It is called conolidine. 

Conolidine, an alkaloid in the alkaloid Tabernaemontana divaricata, plays a special, natural role in relieving pain. It can control the body's sensations through a different mechanism than opioids. This could easily reduce the risk of injury, specifically long-term ones, keeping athletes healthy.

Brief Scientific Overview About Conolidine Pain Relief!

Conolidine is an extremely exciting biomarker of pain. Initially discovered in the Tabernaemontana divaricata plant, conolidine has an already proven, relatively safe and effective mechanism of action for its pain relief. For example, it was found to be as effective as morphine in some preclinical studies. But what makes it so great and so desirable is the method by which it acts, and that is particularly impressive. 

Conolidine does not actually trigger your classic opioid receptors. Instead, this alkaloid works as an atypical chemokine receptor, called ACKR3, where it works in an entirely new way to boost your own natural pain-relieving peptides, like endorphins and enkephalins. When conolidine modifies ACKR3, the resulting pharmacological effects mean your body can rely on its unique ability to control your pain. As the ACKR3 activity increases, the body’s endorphin and enkephalin levels can increase by up to 50%! 

So, naturally you don’t even need to worry about dependence! There’s no implication with opioids either. So it is the natural choice for treating long-term pain, meaning it’s a very safe and sustainable option. Finding this novel mechanism in treating pain is not only a confirmation of Conolidine’s use in traditional medicine. But gives an enormous edge to development of next generation non-addictive therapies in the treatment of pain.

Conolidine Pain Relief For Athletes

Why is Conolidine Pain Relief Important For Athletes?

Non-Addictive Pain Relief

The issues surrounding opioid pain medications are real. They’re very addictive, and they’re quite a risk to become physically dependent. So when an athlete takes an opioid pain drug, they are in danger of overdose. What you may not know is that the only way that conolidine can work is by not binding to the same opioid receptors. That means that it will provide effective pain relief without making you physically dependent. 

Faster Recovery

Basically because of all the training and competitions you 're doing there will be lots of inflammation and muscle soreness. This is normal and can help make people recover faster. Effective pain management can really help with getting back to normal. Conolidine might help with this. That may help athletes do a better job of recovering faster. So there's less down time. Also they might get back to training faster.

No Sedative Side Effects

Many powerful analgesics cause drowsiness and impaired mental functioning. This is not what athletes need. Athletes want to be alert, focused, and aware. Athletes want to be at their best physical and mental performances. It does not appear that conolidine has these sedative effects. This makes it an excellent choice for pain management in a busy training season.

Supports Natural Pain Pathways

Conolidine is not just blocking pain. Its unique mechanism of action is thought to be in synergy with the body's own systems and may increase the availability of the body's native opioid peptides, thus helping the body to combat pain internally. So this is all much more holistic and sustainable in my opinion. It goes beyond just blocking pain signals.

Addresses Chronic and Acute Pain

As athletes, there are some types of pain that can present themselves. These can be acute, sudden sprain, strain, or chronic. This could be tendinitis or muscle aches for a very long time. Conolidine seems promising in terms of both types of pain which makes it a versatile and widely used drug for pain management. It could potentially prove useful over an athlete's entire career from training to competition.

Safer Long-Term Use

There is a lot of pain that an athlete will have to take on a long-term basis. NSAIDs for instance can be dangerous in the long term for an athlete. Stomach ulcers and kidney damage are two of the problems that people can get if they take them for too long. Since conolidine works a different way it could be a better long term option.

The Problem with Traditional Pain Management for Athletes!

Traditional pain management approaches for athletes are very complicated and rarely achieve what they hope to. A few of the most commonly used pain medications have a set of long-term health consequences. That can really hurt an athlete’s overall long-term health and performance. Some of the common medicines used to treat pain and inflammation include problems with the digestive system, lumps, wounds and kidney damage.

Those side effects can be very harmful to an athlete's health and even interfere with the body's natural healing process. Other forms of pain medication are used to treat more serious injuries and are also known to be extremely addictive. It poses a huge risk of dependency that occurs when an athlete is under pressure to recover quickly. These drugs also have negative side effects. They can cause drowsiness and other issues that directly affect an athlete’s ability to train. 

How Conolidine Works For Athletes In Pain Relief?

Targets a Unique Receptor: Conolidine is not an opioid drug in the traditional sense. Opioids directly bind to the classical mu-opioid receptors. Contrary to popular belief, however, conolidine seems to bind to something else. In fact scientific research suggests that it actually binds to a receptor called ACKR3/CXCR7.

Enhances Natural Painkillers: The ACKR3 receptor has a very special job in your body as a " scavenger ". Its main purpose is to bind to and remove the body's natural opioid peptides. The body's natural opioid peptides are things like endorphins and enkephalins. They are the painkillers in your body. By scavenging them ACKR3 protects them from their pain relieving abilities.

Increases Endogenous Opioids: This is where the action of conolidine is so important. By binding and blocking the ACKR3 receptor, conolidine prevents it from scavenging these natural opioids. Therefore allowing more of the body's own painkillers to be produced in the right places. That means that with more natural opioids available they will bind more effectively. 

Avoids Addictive Pathways: Conolidine does not directly affect the classical opioid receptors, and that's how it's non-addictive. It avoids the nasty pathways that lead to tolerance, physical dependence, and then the potentially fatal side effect of respiratory depression. So for athletes, that means they can take the pain away for the long haul without succumbing to addiction, and it's a far safer bet.

Dual-Action Pain Relief: There's evidence that conolidine also has a secondary mechanism. It's been shown to inhibit some voltage-gated calcium channels. In particular, the Cav2.2 channels have a direct role in transmitting pain signals from nerves. By blocking these channels, conolidine could also directly interfere with the transmission of pain. This dual action of stimulating natural painkillers while blocking pain signals makes it one very powerful analgesic.

Proleviate's Conolidine Pain Relief Products Best For Athletes!

• Quickly Pain Relief: Proleviate’s active ingredient, conolidine, is a natural pain reliever. Similar in potency to opioid drugs, and non-addictive, something of tremendous concern to athletes pressed for time after an injury. Which allows for safe long term use without any risk of dependence.

• PEA And Essential Oil for Pain Management: This product was designed to utilize a combination of the conolidine-based mechanism of action with other topical applications. Based on evidence, conolidine acts by enhancing the body’s naturally produced painkilling agent. As well, some of its additional ingredients, like PEA and natural essential oils are also said to have anti-inflammatory and soothing properties.

• Fast-Acting and Long-Lasting: It's actually named Proleviate because it's designed to be " fast acting pain relief " & " last for hours ". For athletes it is crucial to control pain in the run-up to a game, practice as well as to get a good night's sleep to recover better.

• Addresses a Wide Range of Athletic Ailments: The product, conolidine marketed by Proleviate, is widely used for a wide variety of injuries often related to sports. Also for conditions of chronic pain such as tendinitis, sciatica, etc., and a general soreness of muscle and joint due to repetitive stress.

• Supports Overall Health and Recovery: Proleviate has " super antioxidants " claiming to help scavenge free radicals and decrease oxidative damage. Proleviate can make a big difference for athletes who put themselves under intense physical stress. This goes to show a less restrictive approach to recovery as well.

• Holistic Anti-Inflammatory Action: While many pain relievers target one side or the other of inflammation. It seems Proleviate's blend addresses the entire point of inflammation. Conolidine itself has shown some promise as an inflammatory pain reliever. While the addition of PEA and essential oils are added to add to anti-inflammatory properties.

The Bottom Line! 

Conolidine is a pioneering treatment for sport-related pain. This non-addictive, narcotic acterone inhibits receptors in the body that release the painkilling opioids. That allows our bodies to reduce pain with optimum efficiency, in a drug-free, easily administered manner. Through a unique mechanism, conolidine directly activates the body’s pain-relieving organs, with no risk of addiction and serious side effects.